Women often experience sleepless nights and daytime fatigue in the first and third trimesters of their pregnancy. During the first trimester, frequent trips to the bathroom and morning sickness may disrupt sleep. Later in pregnancy, vivid dreams and physical discomfort may prevent deep sleep. After delivery, the new baby's care or the mother's postpartum depression may interrupt sleep.
The decrease in the quantity and quality of the NREM SWS as well as the disturbances of sleep will therefore increase the AB plaques.[29][30] This will first take place at the hippocampus level, from which memory is dependent.[29][30] This will result in cell death at this level and will contribute to diminished memory performances and cognitive decline found in AD disease.[29]
What to do: If you suspect you have a circadian rhythm disorder, take steps to get your body onto a regular sleep schedule. Choose a bedtime and wake-up time that work for you, and follow the same routine each day, even on weekends. This can be tough for those who have to get up early during the week but like to stay up later on weekends, but do your best to craft a compromise between your work week and weekend habits. The important thing is to avoid the trap of sleeping from 10 p.m. to 6 a.m. during the week, then suddenly shifting to late nights and late mornings on the weekends. This will inevitably leave you with insomnia on Sunday night, which in turn sets you up to start the week exhausted on Monday morning.
Stay cool at night. Make sure your bedroom is at the right temperature to help ensure a good night’s sleep. The National Sleep Foundation suggests setting the temperature between 60 and 67 degrees Fahrenheit for optimal sleep. Using cooling sheets and pillows can also help, especially for women in menopause who are experiencing hot flashes at night, says Dr. Alyssa Dweck, assistant clinical professor of obstetrics and gynecology at the Mount Sinai School of Medicine and co-author of “V is for Vagina.”
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